TRANSFORMATION OF FREQUENCY DISPERSION IN ELECTRICAL PARAMETERS OF LIVER TISSUE DURING MEASUREMENT WITH INVASIVE ELECTRODES BASED ON DISTANCE BETWEEN ELECTRODES

Abstract

This study investigates the spectra of electrical impedance in biological tissues (pig liver samples) depending on
experimental conditions. Nyquist plots were obtained using a two-electrodeconfiguration with invasive electrodes by using
different distances between them. Optimalequivalent electrical circuit models of the studied systems were obtained and
processed, and thecomponents of their parameters were calculated. Changes in the frequency dispersion of electrical parameters
were demonstrated. The study concludes on the interdependence of the electric field intensity, the frequencies which were used,
location of the electrodes in the sample, and the ability of impedance spectroscopy to differentiate the state of biological tissue
damage based on its electrical properties.